Day 1

WEDNESDAY November 5

  • From 07.30 REGISTRATIONS OPEN
  • 09:00 – 11:00 Zaal 3 – ESPT Executive Board meeting – Closed Meeting
  • 09:00 – 12:00 Zaal 4 – NVKC / CMBD Symposium (in Dutch)
  • 09:00 – 12:00 Zaal 5 – Apothekers/Huisartsen Symposium (in Dutch)
  • 11:00 – 12:00 Zaal 3 – ESPT GENERAL ASSEMBLY – Closed Meeting
  • 13:00 – 13:30 OPENING of the CONGRESS
    Willem Burger Zaal – Plenary
    Welcome – Ron van Schaik – Local Organizer
    Opening – Mikko Niemi – ESPT President
    Welcome – Tomris Ozben – IFCC President
    Welcome – Stefan Sleijfer – Dean Erasmus MC – University Medical Center Rotterdam
  • 13:30 – 15:20 SESSION 01: CLINICAL IMPLEMENTATION
    Willem Burger Zaal
    Chairs: Ron van Schaik & Jesse Swen
    13:30 Implementation of PGx in the UK: a perspective – Sir Munir Pirmohamed
    (Keynote Lecture)
    13:55 Large scale Pharmacogenomics and Genomics England – Matt Brown
    14:20 Universal clinical implementation of PGx in Spain: results of pilot study in
    public healthcare – Adrian Llerena
    14:45 Implementaton of PGx in The Netherlands: beyond PREPARE – Jesse Swen
    15:10 Abstract: Cost Effectiveness of the PREPARE study – Christina Mitropoulos
  • 15:20 – 15:50 TEA & COFFEE BREAK and POSTERS VIEWING
  • 15:50 – 17:15 SESSION 02: PSYCHIATRY
    Willem Burger Zaal
    Chairs: Adrian Llerena & Birgit Koch
    15:50 Complementary use of PGx and TDM in antidepressive treatment –
    Espen Molden
    16:15 Integration of PGx in psychiatry: experiences from Canada – Daniel Mueller
    16:40 Genome-guided therapeutics in psychiatry: results from the PREPARE
    study and beyond – George Patrinos
    17:05 Abstract: The Dutch P4CARE PGx implementation study for primary care –
    Jesse Swen & Ron van Schaik
    17:15 END of the day
  • From 17:30 OPENING RECEPTION at CITY HALL

Day 2

THURSDAY November 6

  • From 07.30 REGISTRATIONS OPEN
  • 08:00 – 08.45 Willem Burger Zaal – Corporate Workshop
    Agena Bioscience & Platomics
    Towards clinical guideline and IVDR compliant pharmacogenetic
    testing. Implementing pharmacogenetic panel solutions for enhanced
    outcomes and regulatory adherence – Maaike van der Lee
  • 08:00 – 08:45 Zaal 3 – Mini Symposium
    Finnish Society of Clinical Pharmacology
    Clinical implementation of PGx in Finland
    Chair: Mikko Niemi
    08:00 Translating Pharmacogenetics into Clinical Practice: Insights from the
    First 10,000 Patients Genotyped with a 12-Gene Panel – Kaisa Litonius
    08:15 Perceptions of the general public and healthcare professionals on
    pharmacogenetic testing – Noora Kulla
    08:30 Implementing DPYD genotyping in Finland: impact on fluoropyrimidine
    exposure and safety – Antti Hosio
  • 08:00 – 08:45 Zaal 4 – Mini Symposium
    Francophone Network of PGx (RNPGx)
    Using pangenomic data in PGx
    Chair: Nicolas Picard
    08:00 WES and PGx: technical challenges and clinical opportunities – Laure
    Raymond
    08:20 Organizational and regulatory aspects – Louis Lebreton
  • 09:00 – 10:40 SESSION 03: PEDIATRICS
    Willem Burger Zaal
    Chairs: Marieke Coenen & Mikko Niemi
    09:00 Optimal busulfan exposure enhances hematopoietic stem cells
    transplantation outcomes in high-risk pediatric ALL – Marc Ansari
    09:25 Genotype-guided asthma treatment reduces exacerbations in children –
    Anke-Hilse Maitland-van der Zee
    09:50 Reducing aminoglycoside ototoxicity through MT-RNR1 testing –
    William Newman
    10:15 Pharmacogenomics of anti-TNF drugs in pediatric inflammatory bowel
    disease. From research to clinical implementation? – Luis Andrés
    López-Fernández
  • 10:40 – 11:10 TEA & COFFEE BREAK and POSTERS VIEWING
  • 11:10 – 13:00 SESSION 04: ONCOLOGY
    Willem Burger Zaal
    Chairs: Ron Mathijssen & Erika Cecchin
    11:10 Clinical benefit and utility of DPYD and UGT1A1 testing in gastrointestinal
    cancer: beyond single-gene targeted genotyping – Erika Cecchin
    11:35 CYP2D6 and tamoxifen: current status – Matthias Schwab
    12:00 US FDA and guidelines perspectives on DPYD testing – Daniel Hertz
    12:25 New developments in Precision Oncology – Scott Chandler
    12:50 Selected abstract
  • 13:00 – 14:30 WORKING LUNCH / POSTERS VIEWING / BOOTHS VISITS
  • 14:30 – 16:20 SESSION 05: CARDIOVASCULAR
    Willem Burger Zaal
    Chairs: Mikko Niemi & Mia Wadelius
    14:30 Genetics and Precision Medicine in diabetes care – Ewan Pearson
    14:55 Pharmacogenetics of statins – Mikko Niemi
    15:20 CYP2C19 genotyping in patients undergoing percutaneous coronary
    intervention – Jur ten Berg
    15:45 CYP2C19 and clopidogrel in ischemic stroke: current status – Bob
    Roozenbeek
    16:10 Selected abstract
  • 16:20 – 16:50 TEA & COFFEE BREAK and POSTERS VIEWING
  • 16:50 – 18:15 SESSION 06: SOLID ORGAN TRANSPLANTATION
    Willem Burger Zaal
    Chairs: Teun van Gelder & Nicolas Picard
    16:50 Pharmacogenetics in solid organ transplantation: ready for
    implementation? – Teun van Gelder
    17:15 Crosstalk between gut microbiome and immunosuppressive drugs in
    kidney transplantation – Laure Elens
    17:40 Pharmacogenetics in kidney transplantation: from targeted analysis of
    immunosuppressants to the pharmacogenetic passport – Nicolas Picard
    18:05 Selected abstract
    18:15 END of the day
  • 20.00 SOCIAL DINNER
    Location: EUROMAST
    Tickets must be purchased in addition to the registration fee

Day 3

FRIDAY November 7

  • From 07.30 REGISTRATIONS OPEN
  • 08:00 – 08.45 Willem Burger Zaal – Corporate Workshop
    Illumina
    Clinical Implementation of Pharmacogenomics in the Scottish NHS
    Alexander Donay
  • 08:00 – 08:45 Zaal 3 – Mini Symposium
    Spanish Society of Pharmacogenetics and Pharmacogenomics (SEFF)
    Implementation of pharmacogenetics in Spain
    Chair: Cristina Rodríguez-Antona
    08:00 Implementation of the Pharmacogenetic testing catalog of the National
    Healthcare System – Xandra Garcia-Gonzalez
    08:20 SEFF pharmacogenetics guidelines – Juliana Salazar
  • 08:00 – 08:45 Zaal 4 – Mini Symposium
    Italian Society of Pharmacology (SIF)
    Chair: Erika Cecchin
    08:00 Personalized psychiatry: pharmacogenetic insights – Alessio Squassina
    08:15 Integrating pharmacogenetics, drug monitoring and pharmaco-vigilance
    for optimized and safer oral anticancer treatment – Rossana Roncato
    08:30 Pharmacogenomics for children: mechanistic insights from studies on
    extracellular vesicles – Gabriele Stocco
  • 09:00 – 10:40 SESSION 07: GLOBAL PERSPECTIVES
    Willem Burger Zaal
    Chairs: Ann Daly & Sanja Stankovic
    09:00 PGRN: fostering global awareness of pharmacogenomics – Erica Woodahl (PGRN President – Keynote Lecture)
    09:25 Long read sequencing and return of results to biobank participants – Lili Milani
    09:50 Bridging the Gap: understanding missing heritability in pharmacogenomics – Magnus Ingelman-Sundberg
    10:15 Pharmacogenomic diversity in Latin American populations: Brazil as a model case – Guilherme Suarez-Kurtz
  • 10:40 – 11:10 TEA & COFFEE BREAK and POSTERS VIEWING
  • 11:10 – 12:50 SESSION 08: LIQUID BIOPSY
    Willem Burger Zaal
    Chairs: Daan van den Broek & Cristina Rodríguez-Antona
    11:10 Liquid biopsy: current state of the art – Klaus Pantel (Keynote Lecture)
    11:35 Unraveling the biology of metastasis-competent circulating tumor cells: insights into the metastatic cascade – Catherine Alix Panabieres
    12:00 Integrated diagnostics in oncology: bridging tumor markers, liquid biopsy, multi-omics, and imaging: through clinical case studies – Tomris Ozben
    12:25 Implementation of ctDNA analysis: COIN initiative – Daan van den Broek
  • 12:50 – 14:15 WORKING LUNCH / POSTERS VIEWING / BOOTHS VISITS
  • 14:15 – 15:55 SESSION 09: POPULATION, TECHNICAL AND ETHICAL ASPECTS
    Willem Burger Zaal
    Chairs: Maja Matic & Ingolf Cascorbi
    14:15 Genomic Medicine Sweden – implementing precision medicine at national level – Richard Rosenquist
    14:40 Advancing pharmacogenetics testing using long-read sequencing and ONT’s adaptive sampling – Per Hoffmann
    15:05 Unlocking clinical value in pharmacogenetic testing: real-life insights from the lab – Robert Akkers
    15:30 Ethical aspects of PGx as secondary finding – Martina Cornel
  • 15:55 – 16:25 TEA & COFFEE BREAK and POSTERS VIEWING
  • 16:25 – 17:40 SESSION 10: DECISION SUPPORT TOOL & ECONOMICAL ASPECTS
    Willem Burger Zaal
    Chairs: Maaike van der Lee & Vita Dolzan
    16:25 Association for Molecular Pathology’s Recommendations for clinical pharmacogenotyping allele selection – Vicky Prat
    16:50 Advancing personalized medication in primary care through digitalization and pharmacogenetics – Herna Muñoz-Galeano
    17:15 Economics of pharmacogenetic-guided treatments – Dyfrig Hughes
    17:40 ESPT Contribution Award – Mikko Niemi & Ron van Schaik
    17:45 END of the day

Day 4

SATURDAY November 8

  • From 09.00 REGISTRATIONS OPEN
    09:00 – 09:30 Willem Burger Zaal
    Chairs: Birgit Koch & Mikko Niemi
    One test, a life-time of impact: pre-emptive PGx testing in pediatric
    care – Steve J. Melnick and David Mancuso
    09:30 Selected abstract
    09:40 Selected abstract
    09:50 POSTER AWARDS – Chair of Poster Committee
  • 10:00 – 12:00 DISCUSSION FORUM – How to further implement PGx?
    Willem Burger Zaal
    Chair: Ron van Schaik
    TOPICS:
    1. Clinical Implementation of Pharmacogenetics across Europe
    Munir Pirmohamed (UK), Erika Cecchin (IT), Adrian Llerena (ES), Nicolas Picard (FR), Mikko Niemi (FI), Jesse Swen (NL), Mia Wadelius (SE), Lili Milani (EE), Steven Melnick (US), Laure Elens (BE)
    2. Ethical and regulatory aspects
    William Newman (UK), Martina Cornel (NL), Daniel Hertz (US), Jasmine Gratton (EMA)
    3. Industry view on PGx developments
    Claire Bloor (Thermo Fisher), Vicky Pratt (Agena), Cerissa French (Oxford Nanopore), Gino Miele (Gene Drive), Tiffany Morris (Illumina), Daniel Langhoff (Eurofins Genomics), Oliver Goldenberg (Roche)
    4. Which are the needs on PGx research?
    Magnus Ingelman-Sundberg (SE), Ingolf Cascorbi (DE), Erica Woodahl (US) Teun van Gelder (NL), Alexandra Becker (EP PerMed), Birgit Koch (NL)
  • 12:00 END OF THE CONGRESS
    Post Conference Lecture for the General Public
  • 15:00 – 16:00 Studio 8 – Publiekslezing
    Farmacogenetica: uw DNA paspoort voor medicatie! Ron van Schaik