{"id":4037,"date":"2025-09-22T17:10:07","date_gmt":"2025-09-22T15:10:07","guid":{"rendered":"https:\/\/www.esptcongress.org\/?page_id=4037"},"modified":"2025-09-22T17:11:19","modified_gmt":"2025-09-22T15:11:19","slug":"squassina-alessio","status":"publish","type":"page","link":"https:\/\/www.esptcongress.org\/index.php\/squassina-alessio\/","title":{"rendered":"Squassina Alessio"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><p>[vc_row][vc_column width=&#8221;1\/4&#8243;]<style type=\"text\/css\" data-type=\"the7_shortcodes-inline-css\">.shortcode-single-image-wrap.shortcode-single-image-69f8b6a430aaac827ef6dc8edb42d300.enable-bg-rollover .rollover i,\n.shortcode-single-image-wrap.shortcode-single-image-69f8b6a430aaac827ef6dc8edb42d300.enable-bg-rollover .rollover-video i {\n  background: -webkit-linear-gradient();\n  background: linear-gradient();\n}\n.shortcode-single-image-wrap.shortcode-single-image-69f8b6a430aaac827ef6dc8edb42d300 .rollover-icon {\n  font-size: 32px;\n  color: #ffffff;\n  min-width: 44px;\n  min-height: 44px;\n  line-height: 44px;\n  border-radius: 100px;\n  border-style: solid;\n  border-width: 0px;\n}\n.dt-icon-bg-on.shortcode-single-image-wrap.shortcode-single-image-69f8b6a430aaac827ef6dc8edb42d300 .rollover-icon {\n  background: rgba(255,255,255,0.3);\n  box-shadow: none;\n}<\/style><div class=\"shortcode-single-image-wrap shortcode-single-image-69f8b6a430aaac827ef6dc8edb42d300 alignnone  vc_custom_1758553748105 enable-bg-rollover dt-icon-bg-off\" ><div class=\"shortcode-single-image\"><div class=\"fancy-media-wrap  layzr-bg\" style=\"\"><img fetchpriority=\"high\" decoding=\"async\" class=\"preload-me lazy-load aspect\" src=\"data:image\/svg+xml,%3Csvg%20xmlns%3D&#39;http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg&#39;%20viewBox%3D&#39;0%200%20500%20500&#39;%2F%3E\" data-src=\"https:\/\/www.esptcongress.org\/wp-content\/uploads\/2025\/09\/Squassina_foto-500x500.png\" data-srcset=\"https:\/\/www.esptcongress.org\/wp-content\/uploads\/2025\/09\/Squassina_foto-500x500.png 500w, https:\/\/www.esptcongress.org\/wp-content\/uploads\/2025\/09\/Squassina_foto-1000x1000.png 1000w\" loading=\"eager\" sizes=\"(max-width: 500px) 100vw, 500px\" width=\"500\" height=\"500\"  data-dt-location=\"https:\/\/www.esptcongress.org\/index.php\/squassina-alessio\/squassina_foto\/\" style=\"--ratio: 500 \/ 500;\" alt=\"\" \/><\/div><\/div><\/div><div class=\"standard-arrow list-divider bullet-top\"><ul>\n<li>Dr. Squassina Alessio<\/li>\n<\/ul>\n<\/div>[\/vc_column][vc_column width=&#8221;3\/4&#8243;]<div id=\"ultimate-heading-726769f4ef2355de4\" class=\"uvc-heading ult-adjust-bottom-margin ultimate-heading-726769f4ef2355de4 uvc-8756 color-title accent-title-color uvc-heading-default-font-sizes\" data-hspacer=\"no_spacer\"  data-halign=\"left\" style=\"text-align:left\"><div class=\"uvc-heading-spacer no_spacer\" style=\"top\"><\/div><div class=\"uvc-main-heading ult-responsive\"  data-ultimate-target='.uvc-heading.ultimate-heading-726769f4ef2355de4 h2'  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}' ><h2 style=\"--font-weight:theme;\">CV<\/h2><\/div><div class=\"uvc-sub-heading ult-responsive\"  data-ultimate-target='.uvc-heading.ultimate-heading-726769f4ef2355de4 .uvc-sub-heading '  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}'  style=\"font-weight:normal;\">Dr. Squassina is associate professor of Pharmacology at University of Cagliari (Italy), adjunct Assistant Professor at the Department of Psychiatry, Dalhousie University (Halifax, Canada), and Chief of the Laboratory of Pharmacogenomics of the Department of Biomedical Sciences at University of Cagliari. Dr. Squassina trained as a pharmacologist and molecular biologist in Italy and Canada, gaining extensive expertise in the genomics and pharmacogenomics of mental illness. His research activity has been focused on the investigation of the genetic bases of mood disorders, suicide, and response to psychotropic medications. Dr Squassina is involved in many ongoing international projects aimed at disentangling the biological underpinnings of psychiatric disorders and clinical outcomes of pharmacological interventions. He is engaged in educational activities in the field of neuropsychopharmacology and pharmacogenomics, both nationally and internationally. Dr Squassina has published 8 book chapters and more than 180 papers in peer reviewed journals.<\/div><\/div><div id=\"ultimate-heading-47769f4ef2355e2c\" class=\"uvc-heading ult-adjust-bottom-margin ultimate-heading-47769f4ef2355e2c uvc-7753 color-title accent-title-color uvc-heading-default-font-sizes\" data-hspacer=\"no_spacer\"  data-halign=\"left\" style=\"text-align:left\"><div class=\"uvc-heading-spacer no_spacer\" style=\"top\"><\/div><div class=\"uvc-main-heading ult-responsive\"  data-ultimate-target='.uvc-heading.ultimate-heading-47769f4ef2355e2c h2'  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}' ><h2 style=\"--font-weight:theme;\">ABSTRACT<\/h2><\/div><div class=\"uvc-sub-heading ult-responsive\"  data-ultimate-target='.uvc-heading.ultimate-heading-47769f4ef2355e2c .uvc-sub-heading '  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}'  style=\"font-weight:normal;\"><strong>Personalized psychiatry: pharmacogenetic insights<\/strong><\/p>\n<p>The World Health Organization (WHO) reports that nearly a billion people globally live with a mental disorder. These disorders represent a significant cause of disability worldwide, affecting relationships, work, and overall health, and contributing to economic losses and, in severe cases, premature death. Pharmacotherapy represents the gold standard treatment in mental illness, but response is highly heterogeneous, and about one third of patients affected by severe disorders is characterized as treatment resistant. This scenario strongly highlights the need for the identification of better strategies to guide therapeutic interventions.<\/p>\n<p>This presentation will focus on bipolar disorder, a mood disorder affecting about 30 million people worldwide and strongly associated with medical and psycahitric comorbidities and premature death, among which suicide represents one of the first causes. BD is treated with mood stabilizers, with lithium representing the mainstay. However, only 30% of patients respond well to the treatment, with the rest presenting high variability. Compared to other psychiatric medications, the search for molecular predictors of lithium response has been mostly unsuccessful, mainly because its mechanism of action is still not completely understood.\u00a0 This symposium will provide the audience with an overview of the most recent studies on the pharmacogenomics of lithium treatment in BD, presenting the most promising findings.<\/div><\/div>[\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>[vc_row][vc_column width=&#8221;1\/4&#8243;][\/vc_column][vc_column width=&#8221;3\/4&#8243;][\/vc_column][\/vc_row]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-4037","page","type-page","status-publish","hentry","description-off"],"_links":{"self":[{"href":"https:\/\/www.esptcongress.org\/index.php\/wp-json\/wp\/v2\/pages\/4037","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.esptcongress.org\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.esptcongress.org\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.esptcongress.org\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.esptcongress.org\/index.php\/wp-json\/wp\/v2\/comments?post=4037"}],"version-history":[{"count":3,"href":"https:\/\/www.esptcongress.org\/index.php\/wp-json\/wp\/v2\/pages\/4037\/revisions"}],"predecessor-version":[{"id":4045,"href":"https:\/\/www.esptcongress.org\/index.php\/wp-json\/wp\/v2\/pages\/4037\/revisions\/4045"}],"wp:attachment":[{"href":"https:\/\/www.esptcongress.org\/index.php\/wp-json\/wp\/v2\/media?parent=4037"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}