{"id":4028,"date":"2025-09-22T17:06:32","date_gmt":"2025-09-22T15:06:32","guid":{"rendered":"https:\/\/www.esptcongress.org\/?page_id=4028"},"modified":"2025-09-22T17:06:32","modified_gmt":"2025-09-22T15:06:32","slug":"patrinos-george","status":"publish","type":"page","link":"https:\/\/www.esptcongress.org\/index.php\/patrinos-george\/","title":{"rendered":"Patrinos George"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><p>[vc_row][vc_column width=&#8221;1\/4&#8243;]<style type=\"text\/css\" data-type=\"the7_shortcodes-inline-css\">.shortcode-single-image-wrap.shortcode-single-image-74c513456af8af4f4b7f7285a76b833e.enable-bg-rollover .rollover i,\n.shortcode-single-image-wrap.shortcode-single-image-74c513456af8af4f4b7f7285a76b833e.enable-bg-rollover .rollover-video i {\n  background: -webkit-linear-gradient();\n  background: linear-gradient();\n}\n.shortcode-single-image-wrap.shortcode-single-image-74c513456af8af4f4b7f7285a76b833e .rollover-icon {\n  font-size: 32px;\n  color: #ffffff;\n  min-width: 44px;\n  min-height: 44px;\n  line-height: 44px;\n  border-radius: 100px;\n  border-style: solid;\n  border-width: 0px;\n}\n.dt-icon-bg-on.shortcode-single-image-wrap.shortcode-single-image-74c513456af8af4f4b7f7285a76b833e .rollover-icon {\n  background: rgba(255,255,255,0.3);\n  box-shadow: none;\n}<\/style><div class=\"shortcode-single-image-wrap shortcode-single-image-74c513456af8af4f4b7f7285a76b833e alignnone  vc_custom_1758553523644 enable-bg-rollover dt-icon-bg-off\" ><div class=\"shortcode-single-image\"><div class=\"fancy-media-wrap  layzr-bg\" style=\"\"><img fetchpriority=\"high\" decoding=\"async\" class=\"preload-me lazy-load aspect\" src=\"data:image\/svg+xml,%3Csvg%20xmlns%3D&#39;http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg&#39;%20viewBox%3D&#39;0%200%20500%20500&#39;%2F%3E\" data-src=\"https:\/\/www.esptcongress.org\/wp-content\/uploads\/2025\/09\/Patrinos_foto-2-500x500.png\" data-srcset=\"https:\/\/www.esptcongress.org\/wp-content\/uploads\/2025\/09\/Patrinos_foto-2-500x500.png 500w, https:\/\/www.esptcongress.org\/wp-content\/uploads\/2025\/09\/Patrinos_foto-2-1000x1000.png 1000w\" loading=\"eager\" sizes=\"(max-width: 500px) 100vw, 500px\" width=\"500\" height=\"500\"  data-dt-location=\"https:\/\/www.esptcongress.org\/index.php\/speakers\/patrinos_foto-2\/\" style=\"--ratio: 500 \/ 500;\" alt=\"\" \/><\/div><\/div><\/div><div class=\"standard-arrow list-divider bullet-top\"><ul>\n<li>Dr. Patrinos George<\/li>\n<\/ul>\n<\/div>[\/vc_column][vc_column width=&#8221;3\/4&#8243;]<div id=\"ultimate-heading-956969f2fb31304d0\" class=\"uvc-heading ult-adjust-bottom-margin ultimate-heading-956969f2fb31304d0 uvc-7783 color-title accent-title-color uvc-heading-default-font-sizes\" data-hspacer=\"no_spacer\"  data-halign=\"left\" style=\"text-align:left\"><div class=\"uvc-heading-spacer no_spacer\" style=\"top\"><\/div><div class=\"uvc-main-heading ult-responsive\"  data-ultimate-target='.uvc-heading.ultimate-heading-956969f2fb31304d0 h2'  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}' ><h2 style=\"--font-weight:theme;\">CV<\/h2><\/div><div class=\"uvc-sub-heading ult-responsive\"  data-ultimate-target='.uvc-heading.ultimate-heading-956969f2fb31304d0 .uvc-sub-heading '  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}'  style=\"font-weight:normal;\">George P. Patrinos is Director General and Director of Research of the Hellenic Pasteur Institute in Athens, Greece and Professor of Pharmacogenomics and Pharmaceutical Biotechnology in the University of Patras, School of Health Sciences, Department of Pharmacy in Patras, Greece. He also holds adjunct Full Professorships at Erasmus MC, Faculty of Medicine, Department of Pathology (Clinical Bioinformatics Unit) in Rotterdam (the Netherlands) and the United Arab Emirates University, College of Medicine and Health Sciences, Department of Genetics and Genomics. He served for almost 7 years as Chair of the Global Genomic Medicine Collaborative (G2MC) and for 12.5 years as Full Member and Greece\u2019s National representative in the Committee for Human Medicinal Products, Pharmacogenomics Working Party of the European Medicines Agency (EMA).<\/p>\n<p>George is the founder of the Laboratory of Pharmacogenomics and Individualized Therapy, the first officially established academic pharmacogenomics laboratory in Greece. His group has keen interest in research covering disciplines from wet and dry lab and public health genomics projects, all focusing on pharmacogenomics and personalized medicine. In particular, his research interests involve discovery work and clinical implementation of pharmacogenomics, with participation in several prospective pharmacogenomics clinical studies focusing in particular on psychiatry but also cardiology and oncology, genomics of rare disorders and transcriptional regulation of human fetal globin genes. Moreover, George\u2019s group is internationally renowned for its involvement in developing National\/Ethnic Genetic databases to document the genetic heterogeneity in different populations worldwide and of genome informatics tools to translate genomic information into a clinically meaningful format. Also, George\u2019s group has a keen interest in public health genomics to critically assess the impact of genomics to society and public health.<\/p>\n<p>George has more than 360 publications in peer-reviewed scientific journals, some of them in leading scientific journals, such as <em>The Lancet, Lancet EBioMedicine, Nature, <\/em><em>Nature Genetics<\/em>, <em>Nature Rev Genet<\/em>, <em>Nature Mental Health<\/em>, <em>Nature Neuroscience<\/em>, <em>Nucleic Acids Res<\/em>, <em>Genes Dev, iScience<\/em>. Also, he has co-authored and co-edited more than 15 textbooks, among which the renowned textbook \u201cMolecular Diagnostics\u201d, published by Academic Press, now in its 3<sup>rd<\/sup> edition. He is the Editor of \u201cTranslational and Applied Genomics\u201d book series, published by Elsevier and the Editor-In-Chief of the prestigious <em>Pharmacogenomics Journal (TPJ)<\/em>, published by Nature Publishing Group, while he is Associate Editor and member of the editorial board of several high impact scientific journals and a member of several international boards and advisory and evaluation committees.<\/p>\n<p>Apart from that, George is the main co-organizer of the Golden Helix Conferences, an international meeting series on Pharmacogenomics and Personalized Medicine with more than 55 conferences organized in more than 40 cities and 20 countries worldwide.<\/div><\/div><div id=\"ultimate-heading-905169f2fb313050f\" class=\"uvc-heading ult-adjust-bottom-margin ultimate-heading-905169f2fb313050f uvc-195 color-title accent-title-color uvc-heading-default-font-sizes\" data-hspacer=\"no_spacer\"  data-halign=\"left\" style=\"text-align:left\"><div class=\"uvc-heading-spacer no_spacer\" style=\"top\"><\/div><div class=\"uvc-main-heading ult-responsive\"  data-ultimate-target='.uvc-heading.ultimate-heading-905169f2fb313050f h2'  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}' ><h2 style=\"--font-weight:theme;margin-top:50px;\">ABSTRACT<\/h2><\/div><div class=\"uvc-sub-heading ult-responsive\"  data-ultimate-target='.uvc-heading.ultimate-heading-905169f2fb313050f .uvc-sub-heading '  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}'  style=\"font-weight:normal;\"><strong>Genome-guided therapeutics in psychiatry: results from the PREPARE study and beyond<\/strong><\/p>\n<p>George P. Patrinos <sup>1,2,3,4<\/sup><\/p>\n<p><sup>I <\/sup><em>Director General and Director of Research<\/em>, Hellenic Pasteur Institute, Athens, Greece; <sup>2 <\/sup><em>Professor<\/em>; University of Patras School of Health Sciences, Department of Pharmacy, Patras, Greece; <sup>3<\/sup><em> Adjunct Full Professor<\/em>; United Arab Emirates University, College of Medicine and Health Sciences, Department of Genetics and Genomics, Al-Ain, United Arab Emirates; <sup>4<\/sup><em> Adjunct Faculty<\/em>; Erasmus MC, Faculty of Medicine and Health Sciences, Department of Pathology, Clinical Bioinformatics Unit, Rotterdam, the Netherlands. Email: <a href=\"mailto:gpatrinos@upatras.gr\">gpatrinos@upatras.gr<\/a>; general.director@pasteur.gr<\/p>\n<p>&nbsp;<\/p>\n<p>In the post-genomic era, the rapid evolution of high-throughput genotyping technologies and the increased pace of production of genetic research data, are continually prompting the development of appropriate informatics tools, systems and databases as we attempt to cope with the flood of incoming genetic information. Alongside new technologies that serve to enhance data connectivity, emerging information systems should contribute to the creation of a powerful knowledge environment for genotype-to-phenotype information in the context of translational medicine. In the area of pharmacogenomics and personalized medicine, it has become evident that database applications providing important information on the occurrence and consequences of gene variants involved in pharmacokinetics, pharmacodynamics, drug efficacy and drug toxicity, will become an integral tool for researchers and medical practitioners alike. At the same time, two fundamental issues are inextricably linked to current developments, namely data sharing and data protection. In this lecture, the impact of high throughput and next generation sequencing technology and its impact on pharmacogenomics research and clinical implementation of genomic medicine will be addressed. In addition, advances and challenges in the field of pharmacogenomics information systems will be discussed, which in turn prompted the development of an integrated electronic \u2018pharmacogenomics assistant\u2019. The system is designed to provide personalized drug recommendations based on linked genotype-to-phenotype pharmacogenomics data, as well as to support biomedical researchers in the identification of pharmacogenomic related gene variants.<\/div><\/div>[\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>[vc_row][vc_column width=&#8221;1\/4&#8243;][\/vc_column][vc_column width=&#8221;3\/4&#8243;][\/vc_column][\/vc_row]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-4028","page","type-page","status-publish","hentry","description-off"],"_links":{"self":[{"href":"https:\/\/www.esptcongress.org\/index.php\/wp-json\/wp\/v2\/pages\/4028","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.esptcongress.org\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.esptcongress.org\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.esptcongress.org\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.esptcongress.org\/index.php\/wp-json\/wp\/v2\/comments?post=4028"}],"version-history":[{"count":2,"href":"https:\/\/www.esptcongress.org\/index.php\/wp-json\/wp\/v2\/pages\/4028\/revisions"}],"predecessor-version":[{"id":4032,"href":"https:\/\/www.esptcongress.org\/index.php\/wp-json\/wp\/v2\/pages\/4028\/revisions\/4032"}],"wp:attachment":[{"href":"https:\/\/www.esptcongress.org\/index.php\/wp-json\/wp\/v2\/media?parent=4028"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}