{"id":3954,"date":"2025-09-22T15:27:19","date_gmt":"2025-09-22T13:27:19","guid":{"rendered":"https:\/\/www.esptcongress.org\/?page_id=3954"},"modified":"2025-09-22T15:27:19","modified_gmt":"2025-09-22T13:27:19","slug":"litonius-kaisa","status":"publish","type":"page","link":"https:\/\/www.esptcongress.org\/index.php\/litonius-kaisa\/","title":{"rendered":"Litonius Kaisa"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><p>[vc_row][vc_column width=&#8221;1\/4&#8243;]<style type=\"text\/css\" data-type=\"the7_shortcodes-inline-css\">.shortcode-single-image-wrap.shortcode-single-image-a62f51ec836bcddf9d67d40f1c81f18e.enable-bg-rollover .rollover i,\n.shortcode-single-image-wrap.shortcode-single-image-a62f51ec836bcddf9d67d40f1c81f18e.enable-bg-rollover .rollover-video i {\n  background: -webkit-linear-gradient();\n  background: linear-gradient();\n}\n.shortcode-single-image-wrap.shortcode-single-image-a62f51ec836bcddf9d67d40f1c81f18e .rollover-icon {\n  font-size: 32px;\n  color: #ffffff;\n  min-width: 44px;\n  min-height: 44px;\n  line-height: 44px;\n  border-radius: 100px;\n  border-style: solid;\n  border-width: 0px;\n}\n.dt-icon-bg-on.shortcode-single-image-wrap.shortcode-single-image-a62f51ec836bcddf9d67d40f1c81f18e .rollover-icon {\n  background: rgba(255,255,255,0.3);\n  box-shadow: none;\n}<\/style><div class=\"shortcode-single-image-wrap shortcode-single-image-a62f51ec836bcddf9d67d40f1c81f18e alignnone  vc_custom_1758547568220 enable-bg-rollover dt-icon-bg-off\" ><div class=\"shortcode-single-image\"><div class=\"fancy-media-wrap  layzr-bg\" style=\"\"><img fetchpriority=\"high\" decoding=\"async\" class=\"preload-me lazy-load aspect\" src=\"data:image\/svg+xml,%3Csvg%20xmlns%3D&#39;http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg&#39;%20viewBox%3D&#39;0%200%20500%20500&#39;%2F%3E\" data-src=\"https:\/\/www.esptcongress.org\/wp-content\/uploads\/2025\/09\/Litonius_foto-scaled-500x500.jpeg\" data-srcset=\"https:\/\/www.esptcongress.org\/wp-content\/uploads\/2025\/09\/Litonius_foto-scaled-500x500.jpeg 500w, https:\/\/www.esptcongress.org\/wp-content\/uploads\/2025\/09\/Litonius_foto-scaled-1000x1000.jpeg 1000w\" loading=\"eager\" sizes=\"(max-width: 500px) 100vw, 500px\" width=\"500\" height=\"500\"  data-dt-location=\"https:\/\/www.esptcongress.org\/index.php\/speakers\/litonius_foto\/\" style=\"--ratio: 500 \/ 500;\" alt=\"\" \/><\/div><\/div><\/div><div class=\"standard-arrow list-divider bullet-top\"><ul>\n<li>Kaisa Litonius, MD, MA<\/li>\n<\/ul>\n<\/div>[\/vc_column][vc_column width=&#8221;3\/4&#8243;]<div id=\"ultimate-heading-804269f2fc60dcc80\" class=\"uvc-heading ult-adjust-bottom-margin ultimate-heading-804269f2fc60dcc80 uvc-3569 color-title accent-title-color uvc-heading-default-font-sizes\" data-hspacer=\"no_spacer\"  data-halign=\"left\" style=\"text-align:left\"><div class=\"uvc-heading-spacer no_spacer\" style=\"top\"><\/div><div class=\"uvc-main-heading ult-responsive\"  data-ultimate-target='.uvc-heading.ultimate-heading-804269f2fc60dcc80 h2'  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}' ><h2 style=\"--font-weight:theme;\">CV<\/h2><\/div><div class=\"uvc-sub-heading ult-responsive\"  data-ultimate-target='.uvc-heading.ultimate-heading-804269f2fc60dcc80 .uvc-sub-heading '  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}'  style=\"font-weight:normal;\">Kaisa Litonius, MD, MA, is a physician specializing in clinical pharmacology at HUS Helsinki University Hospital and a PhD student at the University of Helsinki. She earned her medical degree in 2021 and a Master of Arts degree in 2015, both from the University of Helsinki. Her doctoral research explores the integration of pharmacogenetic panel testing into healthcare, aiming to enhance personalized medicine in everyday clinical practice. Her key research interests include the real-world impact of pharmacogenetics, drawing on large-scale registry and biobank data.<\/div><\/div><div id=\"ultimate-heading-613969f2fc60dccbe\" class=\"uvc-heading ult-adjust-bottom-margin ultimate-heading-613969f2fc60dccbe uvc-8951 color-title accent-title-color uvc-heading-default-font-sizes\" data-hspacer=\"no_spacer\"  data-halign=\"left\" style=\"text-align:left\"><div class=\"uvc-heading-spacer no_spacer\" style=\"top\"><\/div><div class=\"uvc-main-heading ult-responsive\"  data-ultimate-target='.uvc-heading.ultimate-heading-613969f2fc60dccbe h2'  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}' ><h2 style=\"--font-weight:theme;margin-top:50px;\">ABSTRACT<\/h2><\/div><div class=\"uvc-sub-heading ult-responsive\"  data-ultimate-target='.uvc-heading.ultimate-heading-613969f2fc60dccbe .uvc-sub-heading '  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}'  style=\"font-weight:normal;\"><strong>Translating Pharmacogenetics into Clinical Practice: Insights from the First 10,000 Patients Genotyped with a 12-Gene Panel<\/strong><br \/>\nKaisa Litonius1,2,3, Katriina Tarkiainen1,2,3, Johanna Sistonen1,3,4, Sofia Khan1,3,4, Mikko Niemi1,2,3<\/p>\n<p>1 Department of Clinical Pharmacology, University of Helsinki, Helsinki, Finland<\/p>\n<p>2 Department of Clinical Pharmacology, HUS Diagnostic Center, Helsinki University Hospital, Helsinki, Finland<\/p>\n<p>3 Individualized Drug Therapy Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland<\/p>\n<p>4 Genome Unit, HUS Diagnostic Center, Helsinki University Hospital, Helsinki, Finland<\/p>\n<p><strong>Background and aims<\/strong><br \/>\nPharmacogenetic information can improve medication safety and efficacy, and multigene testing strategy enables the reuse of this data in future clinical decisions. The Helsinki University Hospital Diagnostic Center launched a 12-gene next generation sequencing-based pharmacogenetic panel test in January 2022. The aim of the study is to investigate the real-world implementation of pharmacogenetic panel testing<br \/>\n<strong>Methods<\/strong><br \/>\nIn this retrospective register-based study, we investigated the utilization of the pharmacogenetic panel test and its impact on gene-drug interactions in Helsinki University Hospital patients.<br \/>\n<strong>Results<\/strong><br \/>\nAccording to the preliminary results 9,561 Helsinki University Hospital patients have been tested with the pharmacogenetic panel since January 2022. The medical specialties that utilized the panel most frequently were oncology, psychiatry, cardiology, and gastroenterology. Further results will be presented at the congress.<br \/>\n<strong>Conclusion<\/strong><br \/>\nPharmacogenetic panel testing has been adopted into clinical practice at Helsinki University Hospital, particularly within medical specialties where it can significantly enhance medication safety and therapeutic efficacy.<\/div><\/div>[\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>[vc_row][vc_column width=&#8221;1\/4&#8243;][\/vc_column][vc_column width=&#8221;3\/4&#8243;][\/vc_column][\/vc_row]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-3954","page","type-page","status-publish","hentry","description-off"],"_links":{"self":[{"href":"https:\/\/www.esptcongress.org\/index.php\/wp-json\/wp\/v2\/pages\/3954","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.esptcongress.org\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.esptcongress.org\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.esptcongress.org\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.esptcongress.org\/index.php\/wp-json\/wp\/v2\/comments?post=3954"}],"version-history":[{"count":2,"href":"https:\/\/www.esptcongress.org\/index.php\/wp-json\/wp\/v2\/pages\/3954\/revisions"}],"predecessor-version":[{"id":3956,"href":"https:\/\/www.esptcongress.org\/index.php\/wp-json\/wp\/v2\/pages\/3954\/revisions\/3956"}],"wp:attachment":[{"href":"https:\/\/www.esptcongress.org\/index.php\/wp-json\/wp\/v2\/media?parent=3954"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}